Inducement of apoptosis in HepG2 cells by total extract of Scutellaria barbata and Pseuderanthemum bracteatum Imlay

Hoang Nghia Son, Nguyen Trung Quynh Nhu, Diep Trung Cang, Nguyen Le Huy Thinh, Dang Dang Khoa, Truong Xuan Dai, Nguyen Thi Phuong Thao, Le Thanh Long

Tóm tắt


This study aimed to evaluate the effect of total extract of Scutellaria barbata and Pseuderanthemum bracteatum Imlay on HepG2 cell line. The results showed that total extract reduced HepG2 cell density for 48 hours of treatment. The total extract induced the changes expression of apoptosis-related genes in HepG2 cells including Bcl-2 and caspase family. Moreover, the ratio of apoptotic cells was associated with an increase of total extract concentration.


Từ khóa


apoptosis, gene expression, Pseuderanthemum bracteatum Imlay, Scutellaria barbata, total extract.

Toàn văn:

PDF

Tình trạng

  • Danh sách trống