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Issue: Vol. 23 No. 8 (2026)
Section: Articles
DOI: 10.54607/hcmue.js.23.8.5240(2026)
Date Published: 27/08/2026
Views 179
How to Cite
Huynh, A. D., & Nguyen, C. (2026). In vitro antibacterial activity of Streptomyces sp. SS532 against Aeromonas hydrophila causing disease in striped catfish. Ho Chi Minh City University of Education Journal of Science, 23(8). https://doi.org/10.54607/hcmue.js.23.8.5240(2026)

In vitro antibacterial activity of Streptomyces sp. SS532 against Aeromonas hydrophila causing disease in striped catfish

Huynh Dong A1, Nguyen Hoang Chương1,
1 University of Science, Vietnam National University Ho Chi Minh City, Vietnam

Main Article Content

Abstract

Aeromonas hydrophila is the causative agent of fish septicemia, causing significant economic loss to pangasius farming in Vietnam, which requires effective control of this bacterial pathogen in aquaculture. To address this need, a bacterial strain was isolated from a water sample in Dong Thap province of Vietnam, and it showed antibacterial activity against A. hydrophila in this study. The bacterial isolate was identified as Streptomyces sp. SS532 by morphology and 16S rRNA marker. The antibacterial activity of the SS532 strain was stable at high temperatures, a wide range of pH conditions, and ultraviolet and protease treatments. SS532 showed a relatively broad-spectrum activity on other bacterial pathogens, and this activity was maintained over nine successive generations. The ethyl acetate extract from the culture of SS532 had an MIC value of 640 mg/ml to A. hydrophila, and this extract exhibited a strong anti-biofilm activity starting from 0.04X MIC. The results of this study provide a foundation for further research aimed at applying Streptomyces sp. SS532 in the prevention and control of A. hydrophila-induced septicemia in fish.

Keywords

Streptomyces sp. SS532, antibacterial activity, Aeromonas hydrophila, pangasius, Vietnam

Article Details

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