Preparation of some new schiff bases from 5-nitrovanillin

Abstract

A series of Schiff bases were synthesized successfully based on the condensation reaction between 5-nitrovanillin and aromatic amines in moderate and high yields. The condensation underwent better in DCM solvent, acetic acid catalyst and anhydrous MgSO₄ as a drying agent and increased the yield up to 100 %.These new Schiff bases were determined with ¹H, ¹³C NMR spectral analysis and compound 3a was studied further HSQC, HMBC, NOSY and MS spectra. The C=N bond exists in E conformation.