A STUDY OF LIPID PEROXIDATION INHIBITION OF ENDOPHYTIC FUNGI ISOLATED FROM Kandelia candel DERIVED FROM CAN GIO MANGROVE
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Abstract
Mangrove tree Kandelia candel has been shown to be rich in phenol and flavonoid compounds, resulting in strong antioxidant activity. Therefore, endophytic fungi isolated from this plant can be potentially used to produce antioxidants. In this study, we isolated endophytic fungi from the leaves and roots of K. candel, then investigated basic biological characteristics and the antioxidant activity by reducing power and lipid peroxidation inhibition activity. As a result, four endophytic fungal strains from K. candel leaves and roots were identified and preserved in the Biochemistry and Microbiology Laboratory of the Ho Chi Minh University of Education with the codes of UP-15, UP-16, UP-17, and UP-18. The ethyl acetate extracts from these four strains all show the reducing power. The ethyl acetate extract of the UP-15 strain exhibits the lipid peroxidation inhibition activity with an IC50 of 396 μg/ml.
Keywords
antioxidant activity, Can Gio mangroves, endophytic fungi, Kandelia candel, lipid peroxidation inhibition
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References
Félix, R., Valentão, P., Andrade, P. B., Félix, C., Novais, S. C., & Lemos, M. F. L. (2020). Evaluating the In Vitro Potential of Natural Extracts to Protect Lipids from Oxidative Damage. Antioxidants, 9(3), 231. https://doi.org/10.3390/antiox9030231
Huang, W.-Y., Cai, Y.-Z., Xing, J., Corke, H., & Sun, M. (2007). A potential antioxidant resource: Endophytic fungi from medicinal plants. Economic Botany, 61(1), 14. https://doi.org/10.1663/0013-0001(2007)61[14:APAREF]2.0.CO;2
Oyaizu, M. (1986). Studies on Products of Browning Reaction. The Japanese Journal of Nutrition and Dietetics, 44(6), 307-315. https://doi.org/10.5264/eiyogakuzashi.44.307
Ravindran, C., Naveenan, T., Varatharajan, G. R., Rajasabapathy, R., & Meena, R. M. (2012). Antioxidants in mangrove plants and endophytic fungal associations. Botanica Marina, 55(3), 269-279. https://doi.org/10.1515/bot-2011-0095
Ruma, Kumar, & Prakash. (2013). Antioxidant, anti-inflammatory, antimicrobial and cytotoxic properties of fungal endophytes from Garcinia species. International Journal of Pharmacy and Pharmaceutical Sciences, 5, 889-897.
Siriwach, R., Kinoshita, H., Kitani, S., Igarashi, Y., Pansuksan, K., Panbangred, W., & Nihira, T. (2014). Bipolamides A and B, triene amides isolated from the endophytic fungus Bipolaris sp. MU34. The Journal of Antibiotics, 67(2), 167-170. https://doi.org/10.1038/ja.2013.103
Theantana, T., Kanjanapothi, D., & Lumyong, S. (2012). In vitro Inhibition of Lipid Peroxidation and the Antioxidant System of Endophytic Fungi from Thai Medicinal Plants. Chiang Mai Journal of Science, 39, 429-444.
Wang, Z., Li, Z., Ye, Y., Xie, L., & Li, W. (2016). Oxidative Stress and Liver Cancer: Etiology and Therapeutic Targets. Oxidative Medicine and Cellular Longevity, 2016. https://doi.org/10.1155/2016/7891574
Wei, Zhou, & Lin (2010). Antioxidant activities of extract and fractions from the hypocotyls of the mangrove plant Kandelia candel . International Journal of Molecular Sciences, 11(10), 4080-4093. https://doi.org/10.3390/ijms11104080
Yanishlieva, N. V., Marinova, E., & Pokorný, J. (2006). Natural antioxidants from herbs and spices. European Journal of Lipid Science and Technology, 108(9), 776-793. https://doi.org/10.1002/ejlt.200600127
Zhao, Shan, Mou, & Zhou. (2011). Plant-derived bioactive compounds produced by endophytic fungi. Mini Reviews in Medicinal Chemistry, 11(2), 159-168. https://doi.org/10.2174/138955711794519492