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Date Published: 30/09/2022
Online Published: 30/09/2022
Abstract Views: 334
Views PDF: 149
DOI: https://doi.org/10.54607/hcmue.js.19.9.3563(2022)
Issue
Vol. 19 No. 9 (2022)
Section
Natural Sciences and Technology
How to Cite
Trần , H. P., Huỳnh , T. T. T., Nguyễn , T. T., Nguyễn , D. L., Đỗ , H. N. M., Nguyễn , H. T. L., & Đoàn , L. H. T. (2022). SYNTHESIS OF PYRROLIDINIUM IONIC LIQUID GRAFTED ONTO SILICA GEL AS SOLID-PHASE EXTRACTION SORBENT TO DETERMINE ENROFLOXACIN, NORFLOXACIN, AND DIFLOXACIN ANTIBIOTIC. HCMUE Journal of Science, 19(9), 1494. https://doi.org/10.54607/hcmue.js.19.9.3563(2022)

SYNTHESIS OF PYRROLIDINIUM IONIC LIQUID GRAFTED ONTO SILICA GEL AS SOLID-PHASE EXTRACTION SORBENT TO DETERMINE ENROFLOXACIN, NORFLOXACIN, AND DIFLOXACIN ANTIBIOTIC

Hoàng Phương Trần , Thị Thanh Tâm Huỳnh , Thái Thế Nguyễn , Diệu Linh Nguyễn , Hoàng Ngọc Mai Đỗ , Hồ Thùy Linh Nguyễn , Lê Hoàng Tân Đoàn

Main Article Content

Abstract

We developed a new sorbent using ionic liquids grafted onto silica and applied it as solid-phase extraction in the analysis of fluoroquinolone antibiotic. In this study, 1-methyl-1-octadecylpyrrolidinium bromide was synthesized and grafted onto silica gel. The structure of ionic liquid and ILSPE material was characterized by FT-IR, 1H and 13C NMR, TGA-DT, SEM, BET, and EDX. The material formed between silica gel and ionic liquids via hydrogen bond and van der Waals interaction. Ionic liquid grafted onto silica is an efficient sorbent for the preconcentration of enrofloxacin, norfloxacin, and difloxacin. Finally, it was applied to determine fluoroquinolones in actual samples (egg and shrimp) with high recovery (80-110%).

Keywords

1-methylpyrolidine, antibiotic, fluoroquinolone, ionic liquid, silica gel, solid-phase extraction

Article Details

Author Biography

Hoàng Phương Trần,

Hóa Hữu cơ

References

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