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Date Published: 24/09/2019
Online Published: 24/09/2019
Abstract Views: 194
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DOI: https://doi.org/10.54607/hcmue.js.16.3.2462(2019)
Issue
Vol. 16 No. 3 (2019): Khoa học Tự nhiên và Công nghệ (English)
Section
Articles
How to Cite
Hoang , N. S., Nguyen , T. Q. N., Diep , T. C., Nguyen , L. H. T., Dang , D. K., Truong , X. D., Nguyen , T. P. T., & Le , T. L. (2019). Inducement of apoptosis in HepG2 cells by total extract of Scutellaria barbata and Pseuderanthemum bracteatum Imlay. HCMUE Journal of Science, 16(3), 182. https://doi.org/10.54607/hcmue.js.16.3.2462(2019)

Inducement of apoptosis in HepG2 cells by total extract of Scutellaria barbata and Pseuderanthemum bracteatum Imlay

Nghia Son Hoang , Trung Quynh Nhu Nguyen , Trung Cang Diep , Le Huy Thinh Nguyen , Dang Khoa Dang , Xuan Dai Truong , Thi Phuong Thao Nguyen , Thanh Long Le

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Abstract

This study aimed to evaluate the effect of total extract of Scutellaria barbata and Pseuderanthemum bracteatum Imlay on HepG2 cell line. The results showed that total extract reduced HepG2 cell density for 48 hours of treatment. The total extract induced the changes expression of apoptosis-related genes in HepG2 cells including Bcl-2 and caspase family. Moreover, the ratio of apoptotic cells was associated with an increase of total extract concentration.

Keywords

apoptosis, gene expression, Pseuderanthemum bracteatum Imlay, Scutellaria barbata, total extract.

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