PHYTOCHEMICAL INVESTIGATION OF Flacourtia jangomas STEMS
Main Article Content
Abstract
Flacourtia jangomas has been recognized as a potential medicinal plant in the traditional medicine systems of tropical countries in East and Southeast Asia. This study was conducted to explore the phytochemical constituents of F. jangomas native to Vietnam. Four compounds were isolated from F. jangomas stems, namely β-sitosterol (1), 4-hydroxybenzaldehyde (2), oleanolic acid (3), and methyl ferulate (4). The structures of these compounds were characterized by interpreting NMR data and comparing the results with previously reported data.
Keywords
Salicaceae, Flacourtia jangomas, terpenoids
Article Details
References
Ahmad, J., Wizarat, K., Shamsuddin, K., Zaman, A., & Connolly, J. D. (1984). Jangomolide, a novel limonoid from Flacourtia jangomas. Phytochemistry, 23(6), 1269–1270.
Aklima, J., Mojumder, S., & Sikdar, D. (2014). Total phenolic content, reducing power, antioxidative and anti-amylase activities of five Bangladeshi fruits. Int. Food Res. J., 21(1), 119.
Babu, S., & Jayaraman, S. (2020). An update on β-sitosterol: A potential herbal nutraceutical for diabetic management. Biomed. Pharmacother., 131, 110702.
Cayme, J.-M. C., & Ragasa, C. Y. (2004). Structure elucidation of β-stigmasterol and β-sitosterol from Sesbania grandifora [Linn.] Pers. and β-carotene from Heliotropium indicum Linn. by NMR spectroscopy. Kimika, 20(1), 5–12.
Chen, K.-Y., Chen, Y.-J., Cheng, C.-J., Jhan, K.-Y., Chiu, C.-H., & Wang, L.-C. (2021). 3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products. Biomed. J., 44(6), S258–S266.
Dinda, B., Banerjee, J., Pal, J., & Mahanti, A. (1989). Chemical composition of Flacourtia jangomas fruits. J. Food Sci. Technol., 26(6), 334–336.
Hoque, N., Sohrab, M. H., Afroz, F., Rony, S. R., Sharmin, S., Moni, F., Hasan, C. M., & Rana, M. S. (2020). Cytotoxic metabolites from Thysanolaena maxima Roxb. available in Bangladesh. Clinical Phytoscience, 6(1), 89.
Khare, C. P. (2008). Indian medicinal plants: an illustrated dictionary: Springer Science & Business Media.
Mabberley, D. J. (2008). Mabberley's plant-book. A portable dictionary of plants, their classifications and uses, 3.
Neeharika Dubey, N. D., & Pandey, V. (2013). Ferric reducing power of solvent extracts of fruits of Flacourtia jangomas (Lour.) Raeusch. Life sciences leaflets, 44, 66–71.
Pandey, V., & Dubey, N. (2014). Nutraceutical, pharmaceutical and industrial value of coffee plum: Flacourtia jangomas (Lour.) Raeusch. Everyman's Sci, 49, 98–104.
Parvin, S., Kader, A., Sarkar, G. C., & Hosain, S. B. (2011). In-vitro studies of antibacterial and cytotoxic properties of Flacourtia jangomas. Int. J. Pharm. Sci. Res., 2(11), 2786.
Ramadan, A. M. A. A., Zidan, S. A. H., Shehata, R. M., El-Sheikh, H. H., Ameen, F., Stephenson, S. L., & Al-Bedak, O. A.-H. M. (2024). Antioxidant, antibacterial, and molecular docking of methyl ferulate and oleic acid produced by Aspergillus pseudodeflectus AUMC 15761 utilizing wheat bran. Scientific Reports, 14(1), 3183.
Seebacher, W., Simic, N., Weis, R., Saf, R., & Kunert, O. (2003). Complete assignments of 1H and 13C NMR resonances of oleanolic acid, 18α‐oleanolic acid, ursolic acid and their 11‐oxo derivatives. Magn. Reson. Chem., 41(8), 636–638.
Silva, M. G. V., Vieira, Í. G., Mendes, F. N., Albuquerque, I. L., Dos Santos, R. N., Silva, F. O., & Morais, S. M. (2008). Variation of ursolic acid content in eight Ocimum species from northeastern Brazil. Molecules, 13(10), 2482–2487.
Singh, A. K., & Singh, J. (2010). Evaluation of anti-diabetic potential of leaves and stem of Flacourtia jangomas in streptozotocin-induced diabetic rats. Indian J. Pharmacol., 42(5), 301–305.
Pham, T. N. T., Nguyen, T. Q., Nguyen, V. H., Quach, T. H., Cao, V. D., Nguyen, T. T., Nguyen, T. D. T., & Le, T. D. (2020). Chemical constituents of the stem of Coccinia grandis. IOP Conference Series: Materials Science and Engineering, 736, 022080.
Verma, N., Raghuvanshi, D. S., & Singh, R. V. (2024). Recent advances in the chemistry and biology of oleanolic acid and its derivatives. Eur. J. Med. Chem., 276, 116619.
Vo, V. C. (1997). Từ điển cây thuốc Việt Nam [Dictionary of Vietnamese medicinal plants]. Medical Publishing House.
Zhang, Y., Kong, J., Zhang, J.-H., Wang, L., Zhang, W., Liu, B., & Jiang, Y. Y. (2020). Chemical constituents and pharmacological activities of family Flacourtiaceae: A class of important phytomedicine. Am. J. Chin. Med., 48(02), 287–328.
Aklima, J., Mojumder, S., & Sikdar, D. (2014). Total phenolic content, reducing power, antioxidative and anti-amylase activities of five Bangladeshi fruits. Int. Food Res. J., 21(1), 119.
Babu, S., & Jayaraman, S. (2020). An update on β-sitosterol: A potential herbal nutraceutical for diabetic management. Biomed. Pharmacother., 131, 110702.
Cayme, J.-M. C., & Ragasa, C. Y. (2004). Structure elucidation of β-stigmasterol and β-sitosterol from Sesbania grandifora [Linn.] Pers. and β-carotene from Heliotropium indicum Linn. by NMR spectroscopy. Kimika, 20(1), 5–12.
Chen, K.-Y., Chen, Y.-J., Cheng, C.-J., Jhan, K.-Y., Chiu, C.-H., & Wang, L.-C. (2021). 3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products. Biomed. J., 44(6), S258–S266.
Dinda, B., Banerjee, J., Pal, J., & Mahanti, A. (1989). Chemical composition of Flacourtia jangomas fruits. J. Food Sci. Technol., 26(6), 334–336.
Hoque, N., Sohrab, M. H., Afroz, F., Rony, S. R., Sharmin, S., Moni, F., Hasan, C. M., & Rana, M. S. (2020). Cytotoxic metabolites from Thysanolaena maxima Roxb. available in Bangladesh. Clinical Phytoscience, 6(1), 89.
Khare, C. P. (2008). Indian medicinal plants: an illustrated dictionary: Springer Science & Business Media.
Mabberley, D. J. (2008). Mabberley's plant-book. A portable dictionary of plants, their classifications and uses, 3.
Neeharika Dubey, N. D., & Pandey, V. (2013). Ferric reducing power of solvent extracts of fruits of Flacourtia jangomas (Lour.) Raeusch. Life sciences leaflets, 44, 66–71.
Pandey, V., & Dubey, N. (2014). Nutraceutical, pharmaceutical and industrial value of coffee plum: Flacourtia jangomas (Lour.) Raeusch. Everyman's Sci, 49, 98–104.
Parvin, S., Kader, A., Sarkar, G. C., & Hosain, S. B. (2011). In-vitro studies of antibacterial and cytotoxic properties of Flacourtia jangomas. Int. J. Pharm. Sci. Res., 2(11), 2786.
Ramadan, A. M. A. A., Zidan, S. A. H., Shehata, R. M., El-Sheikh, H. H., Ameen, F., Stephenson, S. L., & Al-Bedak, O. A.-H. M. (2024). Antioxidant, antibacterial, and molecular docking of methyl ferulate and oleic acid produced by Aspergillus pseudodeflectus AUMC 15761 utilizing wheat bran. Scientific Reports, 14(1), 3183.
Seebacher, W., Simic, N., Weis, R., Saf, R., & Kunert, O. (2003). Complete assignments of 1H and 13C NMR resonances of oleanolic acid, 18α‐oleanolic acid, ursolic acid and their 11‐oxo derivatives. Magn. Reson. Chem., 41(8), 636–638.
Silva, M. G. V., Vieira, Í. G., Mendes, F. N., Albuquerque, I. L., Dos Santos, R. N., Silva, F. O., & Morais, S. M. (2008). Variation of ursolic acid content in eight Ocimum species from northeastern Brazil. Molecules, 13(10), 2482–2487.
Singh, A. K., & Singh, J. (2010). Evaluation of anti-diabetic potential of leaves and stem of Flacourtia jangomas in streptozotocin-induced diabetic rats. Indian J. Pharmacol., 42(5), 301–305.
Pham, T. N. T., Nguyen, T. Q., Nguyen, V. H., Quach, T. H., Cao, V. D., Nguyen, T. T., Nguyen, T. D. T., & Le, T. D. (2020). Chemical constituents of the stem of Coccinia grandis. IOP Conference Series: Materials Science and Engineering, 736, 022080.
Verma, N., Raghuvanshi, D. S., & Singh, R. V. (2024). Recent advances in the chemistry and biology of oleanolic acid and its derivatives. Eur. J. Med. Chem., 276, 116619.
Vo, V. C. (1997). Từ điển cây thuốc Việt Nam [Dictionary of Vietnamese medicinal plants]. Medical Publishing House.
Zhang, Y., Kong, J., Zhang, J.-H., Wang, L., Zhang, W., Liu, B., & Jiang, Y. Y. (2020). Chemical constituents and pharmacological activities of family Flacourtiaceae: A class of important phytomedicine. Am. J. Chin. Med., 48(02), 287–328.